Figure 4.

The effects of hydrogen on myelin morphology of sciatic nerve in diabetic rats via Luxol fast blue staining.

Note: (A) Myelin morphology of the sciatic nerve (original magnification 400×). With hydrogen administration, the morphology of the nerve fibers of the sciatic nerve was more complete. There were few cases of looseness and disorder, fiber rupture and breakage (arrows). The Schwann cells were clearly increased, and the axons were more clearly visible. (B, C) Density (B) and average sectional area (C) of myelinated nerve. Data are presented as the mean ± SEM (n = 8). *P < 0.05, vs. control group, #P < 0.05, vs. DM group. C: Control; DM: diabetes mellitus; H₂: hydrogen.