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(A) PPI network diagram. Green indicates upregulated genes, and red-violet indicates downregulated genes. (B–D) Three significant gene clustering modules. (E–F) GO and KEGG enrichment analyses of the modular genes. The size of the circle represents the number of genes involved, and the abscissa represents the frequency of the genes involved in the term total genes. PPI, protein–protein interaction; GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes.
