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. 2022 Sep 28;13:961217. doi: 10.3389/fimmu.2022.961217

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Copyright © 2022 Wang, Li, Xiao, Wu, Chen, Zhu, Feng, Zhuansun, Meng and Feng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Validation of hub genes in the diagnostic value. (A–I) Validation of hub genes in the GSE95095. ROC curves and AUC statistics are used to evaluate the capacity to discriminate CD from healthy controls with excellent sensitivity and specificity. (J) Validation of the integrated diagnostic model in the GSE95095. (K) Validation of the integrated diagnostic model in the GSE117993. These findings indicated these nine hubgenes have excellent diagnostic efficiency in CD. ROC, receiver operating characteristic; AUC, area under the curve; CD, Crohn’s disease.