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. Author manuscript; available in PMC: 2022 Oct 12.
Published in final edited form as: Eur J Clin Invest. 2021 Feb 27;51(7):e13524. doi: 10.1111/eci.13524

Table 1.

Summary results of 95% confidence intervals (CIs) and 95% prediction intervals (PIs) among the 65,931 Cochrane meta-analyses.

Scenario No. of meta-analyses (%)

Interval covering the null value or not
 95% CI not covering the null 18,549 (28.1%)
 95% CI covering the null 47,382 (71.9%)
 95% PI not covering the null 10,097 (15.3%)
 95% PI covering the null 55,834 (84.7%)
Future studies with true effects potentially in opposite directions to meta-results
 95% CI not covering the null but 95% PI covering the null 8,452 (12.8%)
Ratio of PI length over CI length
 1.0 (i.e., PI is identical to CI with no heterogeneity) 22,862 (34.7%)
 1.0–1.2 14,938 (22.7%)
 1.2–1.4 3,537 (5.4%)
 1.4–1.6 2,882 (4.4%)
 1.6–1.8 2,405 (3.6%)
 1.8–2.0 2,037 (3.1%)
 2.0–2.2 1,714 (2.6%)
 2.2–2.4 1,514 (2.3%)
 2.4–2.6 1,418 (2.2%)
 2.6–2.8 1,137 (1.7%)
 2.8–3.0 1,003 (1.5%)
 >3.0 10,484 (15.9%)