Table 3.

Summary of intervention characteristics (N=53).

			Studies, n (%)		References
Purpose
	Prevention	4 (8)		[57,89,93,96]
	Detection	5 (8)		[56,67,73,76,82]
	Treatment	44 (83)		[47-55,58-66,68-72,74,75,77-81,83-88,90-92,94,95,97-99]
Technology
	Web based	20 (38)		[47,49,52,54,58,62,65,74,77,80,81,84-86,88,91-93,96,98]
	Mobile device	17 (32)		[48,53,56,61,67-70,73,75,79,82,87,89,90,94,97]
	Telehealth system	3 (6)		[66,71,95]
	Electronic health records	2 (4)		[72,76]
	Virtual reality	1 (2)		[51]
	Multiple technologies	10 (19)		[50,55,57,59,60,63,64,78,83,99]
Target conditions (mental)
	Depression	36 (68)		[50,52,55-58,60-66,68,69,71-76,78,82-85,87,88,90-93,95,97-99]
	Anxiety	3 (6)		[51,59,79]
	Depression and anxiety	14 (26)		[47-49,53,54,67,70,77,80,81,86,89,94,96]
Target conditions (physical)
	Diabetes	19 (36)		[49,52,61,63,68,72-76,82,85,88,90,91,93,95,98,99]
	Cancer	13 (25)		[51,53,54,70,77,79-81,86,87,94,96,97]
	Hypertension	5 (9)		[47,61,68,75,90]
	Heart failure	3 (6)		[65,71,92]
	Chronic obstructive pulmonary disease	2 (4)		[56,67]
	Stroke	1 (2)		[59]
	Any chronic condition	8 (15)		[50,55,60,62,64,66,69,84]
	Multiple chronic conditions	6 (11)		[48,57,58,78,83,89]
Role of digital health intervention
	Sole intervention	42 (79)		[47-52,55,57,59,60,62-65,68,69,71,73,74,77-99]
	Component of intervention	11 (21)		[53,54,56,58,61,66,67,70,72,75,76]
Intervention components
	Education	30 (57)		[46,49,50,52,55,59,60,63,64,66,67,69,70,73,74,77,78,80,81,83-86,88-91,93,94,96]
	Cognitive behavioral therapy	21 (40)		[47,49,51,52,59,63,65,69,70,74,75,77-81,83,85,92-94]
	Behavioral activation	4 (8)		[46,73,90,91]
	Problem-solving therapy	2 (4)		[73,91]
	Acceptance and commitment therapy	1 (2)		[54]
	Monitoring mental health status or symptoms	14 (26)		[48,49,56,57,63,69,72,78,82,83,85,88,93,98]
	Peer support	9 (17)		[50,55,60,64,66,77,80,81,86]
	Communication with health care providers	9 (17)		[48,67,71,72,77,80,81,86,95]
	Mindfulness	3 (6)		[75,87,97]
	Chat rooms or forums	7 (13)		[66,77,80,81,84,86,96]
Tailoring: tailored to chronic physical conditions			19 (36)		[47,48,52,54,59,65,70,73,74,77,79-81,84,86,88,91,92,96]
Guidance: guided			32 (60)		[46,47,50-52,55,58-60,64-66,69-74,77,78,80,81,83,84,86,90-92,94-96,98]
Guidance provider
	Nurse	9 (17)		[47,65,68,70,71,86,90,92,96]
	Psychologist	6 (11)		[52,57,74,88,91,98]
	Certified peer specialist	4 (8)		[50,55,60,64]
	Trained lay individual	2 (4)		[78,83]
	Allied health professional	2 (4)		[1,2]
	Study staff members	2 (4)		[58,62]
	Physician	1 (2)		[59]
	Multiple professionals	6 (11)		[54,77,80,81,84,99]
	Unclear	1 (2)		[66]
Guidance purpose
	Responding to questions	11 (21)		[47,57,62,65,77,80,81,86,92,95,96]
	Information and feedback	9 (17)		[52,74,80,81,88,95,96,98,99]
	Promoting engagement and adherence	8 (15)		[50,55,57,60,62,64,91,99]
	Sending reminders	7 (13)		[47,52,65,74,88,92,98]
	Offering support	6 (11)		[50,55,60,64,70,91]
	Monitoring symptoms	4 (8)		[72,78,83,95]
	Training to use the intervention	4 (8)		[58,68,90,95]
	Encouragement or positive reinforcement	4 (8)		[57,68,90,95]
	Moderating forum	3 (6)		[80,81,86]
	Counseling	2 (4)		[59,72]
	Check-ins	1 (2)		[54]
	Unclear	2 (4)		[66,84]
Delivery of guidance
	Combination	13 (25)		[50,54,55,57,60,64,72,77,90,91,95,98,99]
	Phone calls	7 (13)		[59,68,71,78,83,84,96]
	Emails	6 (11)		[47,52,65,74,88,92]
	Web-based messages	3 (6)		[80,81,86]
	In-person visits	2 (4)		[58,62]
	WeChat messages	1 (2)		[70]
	Unclear	1 (2)		[66]