Table 5.
Cutoff Value of Inflammatory Biomarkers 72 Hours after ICU Admission
Inflammatory Biomarkers | Normal Reference Range | Cutoff Value | AUC | Sensitivity, % | Specificity, % | P |
---|---|---|---|---|---|---|
CRP | 0–5 mg/mL | 194.9 | 0.646 | 68.4 | 60 | 0.10 |
IL-6 | <6.4 mg/mL | 132.1 | 0.777 | 73.7 | 72 | <0.01* |
d-dimer | <0.2 mg/mL | 2.03 | 0.582 | 47.4 | 96 | 0.35 |
Ferritin | 22–322 ng/mL | 902 | 0.625 | 63.2 | 60 | 0.15 |
LDH | 230–460 U/L | 992.8 | 0.613 | 63.2 | 60 | 0.20 |
Procalcitonin | <0.2 ng/mL | 0.12 | 0.623 | 57.9 | 64 | 0.16 |
*P < 0.05 was considered statistically significant.
AUC, area under the receiver operating characteristic curve; CRP, C-reactive protein; ICU, intensive care unit; IL-6, interleukin 6; LDH, lactate dehydrogenase.