Table 1.
Comparison of demographic and pre-operative clinical data between patients who were found to have a non-complete versus a complete pathological response
| pNCR group n/mean/median (%/SD) n = 128 |
pCR group n/mean/median (%/SD) n = 44 |
p | |
|---|---|---|---|
| Male sex | 83 (64.8%) | 29 (65.9%) | 0.99 |
| Age (years) | 59.3 (12) | 58.3 (12.5) | 0.64 |
| Body mass index (kg/m2) | 26.5 (4.6) | 26.8 (5.4) | 0.69 |
| ASA | 0.78 | ||
| 1 | 1 (0.8%) | 1 (2.2%) | |
| 2 | 77 (60.1%) | 23 (52.3%) | |
| 3 | 50 (39.1%) | 18 (40.9) | |
| Clinical T | |||
| 2 | 22 (17.2%) | 7 (15.9%) | 0.46 |
| 3 | 81 (63.2%) | 32 (72.3%) | |
| 4 | 24 (18.7%) | 5 (11.3%) | |
| Clinical N | 0.52 | ||
| 0 | 40 (31.2%) | 15 (34.1%) | |
| 1 | 75 (58.5%) | 27 (61.3%) | |
| 2 | 13 (10.1%) | 2 (4.5%) | |
| Positive CRM (MRI) | 54 (42.1%) | 17 (38.6%) | 0.72 |
| Tumor location | 0.35 | ||
| Low | 67 (52.3%) | 18 (40.9%) | |
| Mid | 56 (38.9%) | 21 (47.7%) | |
| High | 6 (4.6%) | 4 (9.1%) | |
| Tumor size (cm) | 4.8 (1.7) | 4.6 (2) | 0.57 |
| Extramural vascular invasion | 29 (22.6%) | 4 (9.1%) | 0.07 |
| Tumor shape | 0.46 | ||
| Polypoid | 8 (6.2%) | 5 (11.4%) | |
| Semicircular | 61 (47.6%) | 19 (43.2%) | |
| Annular | 45 (35.1%) | 13 (29.5%) | |
| Tumor grade | 0.69 | ||
| Low | 105 (82%) | 21 (47.7%) | |
| High | 13 (10.2%) | 1 (2.2%) | |
| Sphincter involvement | |||
| Internal | 27 (21%) | 7 (15.9%) | 0.51 |
| External | 7 (5.4%) | 1 (2.2%) | 0.68 |
| Symptomatic presentation | 0.09 | ||
| Obstruction | 9 (7%) | 0 (0%) | |
| Bleeding | 75 (58.6%) | 21 (47.7%) | |
| Pain | 4 (3.1%) | 4 (9.1%) |
ASA, American Society of Anesthesiologists; CRM, circumferential resection margin; MRI, magnetic resonance imaging; pNCR, pathological non-complete response; pCR, pathological complete response