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. 2022 Feb 18;75(8):1379–1388. doi: 10.1093/cid/ciac152

Figure 2.

Figure 2.

Mixed effects model predicted values of mean percentage change in creatinine from baseline over time from 0 to 672 hours (28 days) in entire cohort (A); maximum cell-free hemoglobin (CFHb) ≥77 600 ng/mL (B); maximum CFHb <77 600 ng/mL (C); severe malaria (D); severe malaria and maximum CFHb ≥77 600 ng/mL (E); severe malaria and maximum CFHb <77 600 ng/mL (F); acute kidney injury (G); acute kidney injury and maximum CFHb ≥77 600 ng/mL (H); and acute kidney injury and maximum CFHb <77 600 ng/mL (I). P values below x-axes represent fixed effect interaction term of treatment (acetaminophen) × time. Abbreviation: APAP, acetaminophen.