Table 1.
Differences in Frequency of Sequences With Predicted Half-Maximal Inhibitory Concentrations >1 µg/mL for Broadly Neutralizing Antibodies Comparing Blood/Peripheral Blood Mononuclear Cells With Other Tissues for Each Participant
| Participant | Tissue Group | Broadly Neutralizing Antibody | P Value | Proportion_differences |
|---|---|---|---|---|
| LG01 | Liver | 3BNC117 | .006 | –0.5434 |
| Lymphatic tissue | 3BNC117 | <.001 | –0.4757 | |
| CNS | 3BNC117 | .004 | –0.6862 | |
| LG03 | CNS | PG9 | .004 | 0.5179 |
| CNS | PGT121 | .008 | –0.4230 | |
| LG04 | CNS | 10-1074 | <.001 | –0.7103 |
| Gastrointestinal tract | 1E + 09 | <.001 | –0.5562 | |
| Gastrointestinal tract | PGT121 | <.001 | 0.4348 | |
| Lymphatic tissue | PGT121 | <.001 | 0.4108 | |
| LG05 | Gastrointestinal tract | PG9 | <.001 | –0.68 |
| LG06 | Genitourinary tract | 3BNC117 | .002 | –0.4666 |
| Gastrointestinal tract | PG9 | <.001 | –0.5422 | |
| Genitourinary tract | PG9 | <.001 | –0.5666 |
Abbreviation: CNS, central nervous system.
For participant LG08, no statistically significant differences were observed.
For participant LG12, no blood/ peripheral blood mononuclear cell sequences were available. Shown are only differences that reached statistical significance (P < .05).