TABLE 1.

Enzymes of the classical and modified Embden-Meyerhof pathways encoded in the different genomes of archaea and (hyper)thermophilic bacteria

Genomea	Accession no.
	ATP-GLK	ADP-GLK	ATP-PFK	ADP-PFK	PPi-PFK	GAPDHb	GAPOR
Pfu		AF127910		AF127909		PF1729232	AAC70892
Pho		PH0589		PH1645		PH1830	PH0457
Pab		PAB0967		PAB0213		PAB0257	PA1315
Mja				MJ1604		MJ1146	MJ1185
Mma				Presentc		Present
Afu						AF1732
Mth						MT1009
Hal	AAG20664					AAG18725
Tac	TA0825					TA1103
Sso						SSO0528
Ape	APE2091		APE0012d			APE0171
Tma	TM1469		TM0209		TM0289	TM0688
Aae	AQ1496		AQ1708			AQ1065
Tth	Present		Present			Present

^aGenome analyses were performed on the following organisms euryarchaea, Pfu, P. furiosus; Pho, P. horikoshii; Pab, P. abyssi; Mja, M. jannaschii; Mma, M. mazei; Afu, A. fulgidus; Mth, M. thermoautotrophicum; Hal, Halobacterium sp. strain NRC-1; Tac, T. acidophilum. crenarchaea, Sso, S. solfataricus; Ape, A. pernix. Bacteria, Tma, T. maritima; Aae, A. aeolicus; Tth, T. thermophilus. 

^bGAPDH, glyceraldehyde 3-phosphate dehydrogenase. 

^cPresent, present in the genome but not yet annotated. 

^dAPE0012 was detected using the N-terminal amino acid sequence of the ATP-PFK from Desulfurococcus amylolyticus (6) and was recently experimentally confirmed (21).