Table 2.
AN hyperactivations and hypoactivation relative to HC
| Region | Hemisphere | BA | MNI coordinates | ALE | P | Z | Cluster size | ||
|---|---|---|---|---|---|---|---|---|---|
| x | y | z | Vol/mm3 | ||||||
| AN > HC | |||||||||
| Cerebellum | R | – | 14 | − 74 | − 16 | 7.672E-03 | 1.25E-04 | 3.663 | 68,432 |
| Cerebellum | R | – | 11 | − 35 | − 26 | 7.666E-03 | 1.25E-04 | 3.663 | |
| Cerebellum | R | – | 34 | − 46 | − 20 | 7.662E-03 | 1.28E-04 | 3.656 | |
| Cerebellum | R | – | 30 | − 74 | − 26 | 7.570E-03 | 1.37E-04 | 3.638 | |
| Lingual gyrus | R | 18 | 22 | − 74 | − 2 | 7.416E-03 | 1.58E-04 | 3.602 | |
| Precuneus | R | 31 | 32 | − 76 | 24 | 6.862E-03 | 3.03E-04 | 3.429 | |
| Medial frontal gyrus | L | 9 | 8 | 47 | 12 | 6.967E-03 | 2.70E-04 | 3.460 | 38,704 |
| Superior frontal gyrus | R | 10 | 28 | 64 | 0 | 7.144E-03 | 1.97E-04 | 3.544 | |
| Middle frontal gyrus | R | 46 | 44 | 42 | 10 | 6.646E-03 | 5.13E-04 | 3.283 | |
| Cingulate gyrus | L | 24 | − 0.3 | 6.3 | 46 | 3.60E-04 | 3.19E-02 | 1.853 | 32,784 |
| Cerebellum | L | – | − 42 | − 72 | − 22 | 7.829E-03 | 3.02E-05 | 4.011 | 22,944 |
| Cerebellum | L | – | − 18 | − 74 | − 24 | 7.592E-03 | 1.33E-04 | 3.646 | |
| HC > AN | |||||||||
| Striatum | R | – | 33 | 8 | 4 | 6.707E-03 | 2.52E-04 | 3.479 | 31,240 |
| Inferior frontal gyrus | R | 47 | 36 | 23 | − 11 | 6.529E-03 | 3.73E-04 | 3.372 | |
| Amygdala | L | – | − 21 | − 10 | − 11 | 6.519E-03 | 3.73E-04 | 3.372 | 30,656 |
| Thalamus | L | – | − 3 | − 7 | − 5 | 6.336E-03 | 4.31E-04 | 3.332 | |
| Lingual gyrus | R | 18 | 14 | − 86 | − 6 | 6.618E-03 | 2.75E-04 | 3.455 | 17,200 |
| Parahippocampal gyrus | L | 30 | − 9 | − 40 | 1 | 6.519E-03 | 3.73E-04 | 3.372 | 16,776 |
| Insula | L | – | − 30 | 17 | 7 | 6.519E-03 | 3.73E-04 | 3.372 | 16,768 |
| Inferior parietal lobule | L | 40 | − 34 | − 44 | 50 | 7.831E-03 | 8.12E-05 | 3.771 | 14,552 |
| Cerebellum | L | – | − 32 | − 78 | − 20 | 7.958E-03 | 4.03E-05 | 3.942 | 14,480 |
| Cerebellum | R | – | 20 | − 44 | − 20 | 8.638E-03 | 9.62E-06 | 4.273 | 14,040 |
| Insula | R | 13 | 48 | − 24 | − 2 | 8.234E-03 | 1.58E-05 | 4.162 | 14,016 |
| Inferior parietal lobule | R | 40 | 49 | − 31 | 48 | 7.876E-03 | 7.71E-05 | 3.784 | 13,344 |
| Precuneus | R | 19 | 35 | − 73 | 36 | 7.876E-03 | 7.71E-05 | 3.784 | 13,240 |
Anatomical locations and spatial coordinates of ALE analysis showing significant activations (with a cluster-defining threshold of p < 0.05, FWE corrected for multiple comparisons)
BA brodmann area