Table 3.
BN hyperactived and hypoactivated brain regions when looking at food images relative to HC
| Region | Hemisphere | BA | MNI coordinates | ALE | P | Z | Cluster size | ||
|---|---|---|---|---|---|---|---|---|---|
| x | y | z | Vol/mm3 | ||||||
| BN > HC | |||||||||
| Insula | L | – | − 36 | − 6 | − 8 | 7.563E-03 | 9.06E-05 | 3.744 | 42,184 |
| Insula | L | 13 | − 42 | 2 | − 4 | 7.532E-03 | 9.16E-05 | 3.741 | |
| Insula | L | – | − 38 | 0 | 4 | 7.374E-03 | 1.01E-04 | 3.716 | |
| Striatum | L | – | − 26 | − 4 | 2 | 7.369E-03 | 1.01E-04 | 3.716 | |
| Insula | L | 13 | − 44 | 6 | − 4 | 7.368E-03 | 1.01E-04 | 3.716 | |
| Insula | L | 13 | − 40 | 12 | − 4 | 7.361E-03 | 1.22E-04 | 3.669 | |
| Striatum | L | − 18 | 4 | − 10 | 7.361E-03 | 1.22E-04 | 3.669 | ||
| Middle temporal gyrus | L | 37 | − 48 | − 44 | − 4 | 7.144E-03 | 1.84E-04 | 3.562 | 22,272 |
| Fusiform gyrus | L | 37 | − 40 | − 64 | − 8 | 6.444E-03 | 5.52E-04 | 3.263 | |
| Cerebellum | R | – | 4 | − 42 | − 8 | 7.876E-03 | 6.84E-05 | 3.814 | 21,424 |
| Cerebellum | R | – | 4 | − 58 | − 22 | 6.471E-03 | 5.46E-04 | 3.265 | |
| Cuneus | L | 17 | − 22 | − 80 | 12 | 8.430E-03 | 2.26E-05 | 4.080 | 21,040 |
| Superior Occipital gyrus | L | 19 | − 34 | − 72 | 34 | 7.144E-03 | 1.84E-04 | 3.562 | |
| Anterior cingulate | R | 32 | 12 | 42 | 21 | 7.331E-03 | 1.40E-04 | 3.633 | 18,504 |
| Superior frontal gyrus | R | 8 | 20 | 44 | 48 | 7.144E-03 | 1.84E-04 | 3.562 | |
| Cuneus | R | 17 | 24 | − 80 | 12 | 8.371E-03 | 2.32E-05 | 4.073 | 18,072 |
| Lingual gyrus | R | 19 | 26 | − 70 | 2 | 7.157E-03 | 1.55E-04 | 3.607 | |
| HC > BN | |||||||||
| Middle frontal gyrus | L | 10 | − 44 | 44 | − 8 | 7.951E-03 | 4.88E-05 | 3.896 | 14,464 |
| Middle frontal gyrus | L | 46 | − 48 | 28 | 24 | 8.026E-03 | 2.99E-05 | 4.014 | 14,296 |
| Precuneus | L | 7 | − 27 | − 59 | 42 | 7.876E-03 | 7.88E-05 | 3.779 | 14,176 |
| Precuneus | R | 5 | 11 | − 41 | 66 | 7.876E-03 | 7.88E-05 | 3.779 | 14,168 |
| Middle temporal gyrus | R | 21 | 58 | − 26 | − 10 | 8.453E-03 | 1.01E-05 | 4.263 | 13,976 |
| Superior temporal gyrus | L | 22 | − 54 | − 16 | − 2 | 8.374E-03 | 1.40E-05 | 4.189 | 13,928 |
| Middle temporal gyrus | R | 39 | 48 | − 68 | 30 | 8.482E-03 | 6.29E-06 | 4.367 | 11,216 |
Anatomical locations and spatial coordinates of ALE analysis showing significant activations (with a cluster-defining threshold of p < 0.05, FWE corrected for multiple comparisons)
BA brodmann area