Table 3.
Immunofluorescence titre of autoantibody reactivity on hypothalamic cells from AN serum patients, before and after depletion by recombinant human Ghrelin, recombinant human POMC, recombinant human AGRP, or recombinant human α-MSH soluble molecules
Baseline (1:x) | + Ghrelin (1:x) | + POMC (1:x) | + ARGP (1:x) | + α-MSH (1:x) | |
---|---|---|---|---|---|
1 | 80 | 80 | 80 | 80 | 40 |
2 | 40 | 20 | 20 | 20 | 10 |
3 | 40 | 20 | 40 | 20 | 20 |
4 | 80 | 40 | 20 | 40 | 10 |
5 | 40 | 40 | 20 | 40 | 20 |
6 | 40 | 20 | 20 | 20 | 0 |
7 | 40 | 20 | 20 | 20 | 10 |
8 | 40 | 20 | 20 | 20 | 20 |
9 | 80 | 40 | 40 | 40 | 20 |
10 | 40 | 40 | 40 | 40 | 10 |
11 | 20 | 10 | 0 | 10 | 0 |
12 | 80 | 40 | 40 | 40 | 20 |
13 | 80 | 40 | 40 | 40 | 40 |
14 | 80 | 40 | 40 | 40 | 40 |
15 | 10 | 10 | 10 | 10 | 0 |
16 | 10 | 0 | 0 | 0 | 0 |
17 | 20 | 10 | 10 | 10 | 0 |
18 | 80 | 40 | 20 | 20 | 20 |
19 | 80 | 20 | 40 | 40 | 40 |
20 | 80 | 40 | 40 | 40 | 40 |
21 | 80 | 40 | 40 | 40 | 20 |
22 | 80 | 40 | 40 | 40 | 20 |