Table 2.
Demographics neonates with a central-line
| Year | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | P valuea |
|---|---|---|---|---|---|---|---|---|---|---|
| Number of neonates with a central-line | 119 (69%) | 120 (66%) | 110 (62%) | 96 (65%) | 116 (62%) | 75 (44%) | 81 (53%) | 86 (47%) | 88 (51%) | < 0.001 |
| Age at central-line insertion | 0.75 [0.47, 1.04] | 0.74 [0.53, 0.96] | 0.87 [0.63, 1.04] | 0.75 [0.58, 0.92] | 0.90 [0.59, 1.35] | 0.97 [0.68, 1.37] | 0.88 [0.60, 1.09] | 0.92 [0.57, 1.55] | 0.93 [0.67, 1.45] | < 0.001 |
| Age at central-line removal | 7 [5, 10] | 8 [6, 10] | 8 [6, 10] | 8 [6, 12] | 9 [6, 12] | 10 [7, 12] | 9 [6, 12] | 10 [7, 13] | 9 [7, 12] | < 0.001 |
| Line-days per neonate | 6.2 [3.8, 8.4] | 6.6 [4.5, 8.8] | 6.8 [4.5, 8.9] | 7.2 [5.0, 10.1] | 6.6 [4.5, 9.2] | 6.8 [4.9, 9.8] | 7.4 [4.9, 9.4] | 7.8 [5.8, 11.0] | 7.2 [5.7, 10.3] | 0.002 |
| Total line-days | 862 | 835 | 793 | 792 | 852 | 594 | 660 | 787 | 764 | – |
| Neonates with CLABSI | 10 (8.4%) | 8 (6.7%) | 7 (6.4%) | 19 (20%) | 13 (11%) | 10 (13%) | 8 (9.9%) | 10 (12%) | 12 (14%) | 0.07 |
| CLABSI incidence per 1,000 line-days | 11.6 | 9.58 | 8.83 | 25.3 | 15.3 | 16.8 | 12.1 | 13.9 | 15.7 | 0.27b |
Results are presented as N, n (%), median [IQR] or N normalized per 1000 line-days. Bold emphasis corresponds to the p-values which are statistically significant (i.e. p < 0.05)
CLABSI, central-line associated bloodstream infection
aP values corresponds to the chi-square test of independence and Kruskal–Wallis test, as appropriate
bP values correspond to ANOVA test of the increase in model fit by adding year to Poisson regression