Table 4.

Comparison of heart rate (x̅ ± sd)

Indicator	Group	T1	T2	T3	T4	T5
Heart rate (beat/min)	Dexmedetomidine group (n=45)	81.23±8.21	64.30±5.32a,b	55.37±4.68a,b	53.21±2.93a,b	62.28±8.34a,b
	Control group (n=45)	82.51±8.33	71.41±6.74a	69.33±6.82a	67.54±4.26a	73.36±6.81a

Note: Compared with T1;

^aP<0.05.

Compared with control group;

^bP<0.05.

F_time=220.036, P_time=0.000; F_inter-group=3.389, P_inter-group=0.003; F_interaction=0.937, P_interaction=0.393. T1: 5 min before induction of anesthesia in recumbent position, T2: 5 min after CO₂ pneumoperitoneum in Trendelenburg position, T3: 30 min after CO₂ pneumoperitoneum in Trendelenburg position, T4: 60 min after CO₂ pneumoperitoneum in Trendelenburg position, T5: 5 min after the close of pneumoperitoneum in recumbent position.