Table 4.

Differential expression of miRNA in serum of the four groups (x̅±s)

Item	Periodontal group (n=26)	T2DM group (n=24)	Comorbid group (n=22)	Healthy group (n=25)	F	P
Hsa-miR-141	1.44±0.24	1.42±0.26	1.39±0.27	1.33±0.26	0.876	0.456
Hsa-miR-201a	1.22±0.20	1.20±0.21	1.25±0.20	1.20±0.18	0.327	0.806
Hsa-miR-21c	1.89±0.23	1.85±0.21	1.84±0.22	1.83±0.20	0.379	0.768
Hsa-miR-22b	1.75±0.26	1.80±0.30	1.77±0.28	1.74±0.30	0.210	0.889
Hsa-miR-223	3.20±0.36a	3.05±0.33a,b	3.90±0.48a,b	2.06±0.38	90.304	<0.001
Hsa-miR-200b	3.11±0.17a	2.78±0.11a,b	3.40±0.29a,b	2.50±0.14	104.023	<0.001
Hsa-miR-23a	2.20±0.19	2.18±0.22	2.21±0.23	2.23±0.30	0.187	0.905
Hsa-miR-106	2.18±0.21a	2.19±0.24a	2.48±0.22a,b	1.98±0.20	20.728	<0.001
Hsa-miR-103	2.22±0.27a	2.20±0.25a	2.48±0.26a,b	2.13±0.20	8.840	<0.001
Hsa-miR-158	2.23±0.21	2.26±0.22	2.30±0.23	2.29±0.20	0.534	0.661
Hsa-miR-203	1.36±0.11	1.38±0.12	1.39±0.13	1.33±0.14	1.070	0.366

^aindicates that compared with the healthy group, P<0.05.

^bindicates that compared with another group of patients, P<0.05.