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. 2022 Sep 15;14(9):6095–6106.

Figure 7.

Figure 7

Artemether enhances the antioxidant stress system to protect against iron-mediated tubular injury in mice with T1D. A-C: Representative western blot images and quantification of xCT and GPX4. D, E: Relative mRNA levels of xCT and GPX4. F: Representative images of IHC staining of xCT in each group. G: Representative images of IHC staining of GPX4 in each group. For each group, n=4-6. Scale bar, 200 μm. **P<0.01 and ***P<0.001 vs. the T1D-ctrl group. #P<0.05 vs. the STZ group.