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. 2022 Oct 12;13:6000. doi: 10.1038/s41467-022-33536-x

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a Power spectrum (0–400 Hz) and time-resolved power spectrum (40–400 Hz) of the LFP recorded from the CA1 pyramidal layer of a mouse, centered at the natural fluctuations of Ach levels (troughs and peaks, respectively). b Same as in b but during waking. Note the absence of ripples (>100 Hz) during Ach peaks, whereas highest gamma power (40–120 Hz) is present at the highest levels of Ach release. Note also the different calibration of the power panels and averaged Ach signal. Based on >50 average epochs. c Average cross-frequency power comodulogram of the LFP from the CA1 pyramidal layer in a macaque. Note the inverse correlation between ripple and beta/gamma (20–80 Hz) frequency bands. a, b Reproduced from ref. 7, and c reproduced from ref. 140, CC BY-ND 4.0 (https://creativecommons.org/licenses/by-nd/4.0/).