Table 2.

Risk of bias in human trials examining yohimbine in alcohol research.

	Selection bias		Performance bias	Detection bias	Attrition bias	Reporting bias	Other bias
	Random sequence generation	Allocation concealment
Krystal et al. 1994
Ranking	Low-risk	Low-risk	Low-risk	Low-risk	Low-risk	Low-risk
Krystal et al. 1996
Ranking	Low-risk	Low-risk	Low-risk	Low-risk	High-risk	Low-risk
Krystal et al. 1997
Ranking	Low-risk	Low-risk	Low-risk	Low-risk	Low-risk	High-risk
McDougle et al. 1995
Ranking	Low-risk	Low-risk	Low-risk	Low-risk	Low-risk	Low-risk	Unclear
Umhau et al. 2011
Ranking	Low-risk	Low-risk	Low-risk	Low-risk	Low-risk	Low-risk	Low-risk

Clinical trials were assessed for selection, performance, detection, attrition, reporting biases, and described as high-risk, low-risk, or unclear [29].