Table 2.
Interaction effects on the association of cognitive decline, stratified as continuous categories, with mortality after adjustments for corresponding covariates.
Subgroup | No. of patients | HR (95% CI) | HR (95% CI) for interaction | P for interaction |
---|---|---|---|---|
Total | 14,891 | 1.04 (1.04, 1.05) | ||
Age | 0.99 (0.99, 1.00) | 0.277 | ||
Aged 80–89 | 7220 | 1.05 (1.04, 1.06) | ||
Aged 90+ | 7671 | 1.04 (1.03, 1.05) | ||
Sex | 1.01 (1.00, 1.01) | 0.013 | ||
Male | 6058 | 1.04 (1.03, 1.04) | ||
Female | 8833 | 1.05 (1.04, 1.05) | ||
High BP | 1.00 (0.99, 1.02) | 0.082 | ||
Yes | 8589 | 1.05 (1.04, 1.06) | ||
No | 6259 | 1.04 (1.03, 1.05) | ||
Hypertension | 1.01 (1.00, 1.01) | 0.004 | ||
Yes | 2224 | 1.06 (1.05, 1.08) | ||
No | 12,667 | 1.04 (1.03, 1.05) | ||
Aged 80–89 | 1.01 (0.99, 1.02) | 0.173 | ||
Non-high BP | 4049 | 1.04 (1.03, 1.05) | ||
High BP | 3171 | 1.06 (1.04, 1.07) | ||
Aged 90+ | 1.00 (1.00, 1.01) | 0.002 | ||
Non-high BP | 4547 | 1.04 (1.03, 1.05) | ||
High BP | 3124 | 1.04 (1.03, 1.05) |