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. 2022 Oct 12;12:17061. doi: 10.1038/s41598-022-21437-4

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Local regression curves (LOESS; comparable to Fig. 4) depending on the flow rates (1–500 ml/min). The averaged individual values, which are the basis of the regression analysis, have been omitted for visual clarity. No or minor cooling effects could be demonstrated for the test series with a perfusion rate of 1 ml/min. From a flow rate of 2 ml/min, moderate cooling effects occurred at a distance of 7.5 mm from the ablation centre in all test series. Moderate to severe cooling effects occurred at the ablation centre above a flow rate of 10 ml/min.