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. 2022 Apr 27;47(12):2140–2149. doi: 10.1038/s41386-022-01327-z

Fig. 4. Males and females: change in mIPSCs following bath application of selective CRFR1-receptor antagonist, NBI (1 µM).

Fig. 4

mIPSC frequency activity before and after CRFR1 blockade, reported as % change in baseline activity, and representative traces in (A) males and (B) females. Only PAE males demonstrate significant tonic activation of CRFR1. *indicates significant effect of exposure (p < 0.05) # signifies significant difference from 0.