Table 11.
Cox Proportional HRs of All Causes of Mortality in Fully Adjusted Models in the Stacked CanCHEC With Both PM2.5 and Ox Together in the Same Modela,b
Cause of Death | Deathsc (n) | Pollutant | Coeff | SE | HRd | 95% CI | |
---|---|---|---|---|---|---|---|
Nonaccidental | 1,253,300 | PM2.5 | 0.0022 | 0.0006 | 1.022 | 1.010 | 1.035 |
Ox | 0.0053 | 0.0003 | 1.054 | 1.048 | 1.060 | ||
Cardiovascular | 390,600 | PM2.5 | 0.0024 | 0.0011 | 1.024 | 1.002 | 1.047 |
Ox | 0.0116 | 0.0005 | 1.123 | 1.112 | 1.135 | ||
Cerebrovascular | 72,900 | PM2.5 | –0.0014 | 0.0026 | 0.986 | 0.937 | 1.037 |
Ox | 0.0105 | 0.0012 | 1.110 | 1.084 | 1.138 | ||
Heart failure | 20,500 | PM2.5 | 0.0358 | 0.0049 | 1.431 | 1.299 | 1.575 |
Ox | –0.0296 | 0.0023 | 0.744 | 0.711 | 0.779 | ||
Diabetes | 41,100 | PM2.5 | –0.0115 | 0.0036 | 0.891 | 0.831 | 0.956 |
Ox | 0.0287 | 0.0017 | 1.333 | 1.290 | 1.377 | ||
Ischemic heart disease | 215,700 | PM2.5 | 0.0011 | 0.0015 | 1.011 | 0.982 | 1.040 |
Ox | 0.0175 | 0.0007 | 1.191 | 1.175 | 1.208 | ||
Lung cancer | 129,200 | PM2.5 | 0.0090 | 0.0020 | 1.095 | 1.053 | 1.138 |
Ox | –0.0090 | 0.0009 | 0.914 | 0.897 | 0.930 | ||
Respiratory | 105,900 | PM2.5 | 0.0010 | 0.0022 | 1.010 | 0.967 | 1.055 |
Ox | 0.0056 | 0.0010 | 1.058 | 1.037 | 1.079 | ||
COPD | 61,400 | PM2.5 | –0.0061 | 0.0029 | 0.941 | 0.889 | 0.995 |
Ox | 0.0106 | 0.0013 | 1.112 | 1.083 | 1.141 | ||
Pneumonia | 25,600 | PM2.5 | 0.0175 | 0.0044 | 1.191 | 1.094 | 1.298 |
Ox | 0.0003 | 0.0021 | 1.003 | 0.963 | 1.045 | ||
Kidney failure | 15,000 | PM2.5 | 0.0124 | 0.0059 | 1.132 | 1.008 | 1.271 |
Ox | –0.0139 | 0.0027 | 0.870 | 0.825 | 0.918 |
a HRs are given for each pollutant in two-pollutant models. HRs scaled to IQRs are provided in Appendix Table D.4; available on the HEI website.
b Fully adjusted models are stratified by sex, age (5-year categories), and recent immigrant status and are adjusted for income adequacy quintile, visible minority status, Indigenous identity, educational attainment, labor-force status, marital status, occupation, and ecological covariates of community size, airshed, urban form, and four dimensions of Can-Marg (instability, deprivation, dependency, and ethnic concentration).
b Deaths were rounded to the nearest 100 for confidentiality.
c HRs are presented as per 10-μg/m3 increase.