Table 2.
Test | wild-type | GluA1C811S | p value | |||
---|---|---|---|---|---|---|
Physical characterization | body weight (g) | 43.6 ± 1.1 | 43.4 ± 0.9 | 0.91 | ||
rectal temperature (°C) | 34.3 ± 0.2 | 34.1 ± 0.2 | 0.46 | |||
Neuromuscular strength | grip strength (N) | 0.68 ± 0.03 | 0.63 ± 0.03 | 0.26 | ||
wire hang (s) | 4.84 ± 0.54 | 4.02 ± 1.04 | 0.50 | |||
Sensory function | acoustic startle response (a.u.) | 110 dB | 0.76 ± 0.10 | 0.95 ± 0.13 | 0.50 | |
120 dB | 1.01 ± 0.12 | 1.05 ± 0.13 | ||||
prepulse inhibition (%) | 74–110 dB | 41.0 ± 8.0 | 42.7 ± 6.6 | 0.83 | ||
78–110 dB | 60.0 ± 5.3 | 61.5 ± 3.8 | ||||
74–120 dB | 31.4 ± 6.2 | 26.5 ± 7.9 | 0.51 | |||
78–120 dB | 55.2 ± 4.8 | 49.9 ± 5.4 | ||||
Hot plate | latency to avoid (s) | 7.24 ± 0.58 | 7.94 ± 0.64 | 0.43 |
The p values represent the genotype effect in the ANOVA. All values are represented as the mean ± SEM.