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. 2022 Oct 12;12:17104. doi: 10.1038/s41598-022-21277-2

Table 2.

In vitro cytotoxicity (IC50, µM) of the tested compound and DOX against human normal cell line WI38.

Comp. no. WI38a IC50 (µM) Comp. no WI38 IC50 (µM)
3 78.52 ± 3.8 9 48.18 ± 2.8
5 63.97 ± 3.1 10 67.74 ± 3.4
7 > 100 11 43.25 ± 2.9
8 48.18 ± 2.8 12 56.45 ± 3.2
DOX 4.50 ± 0.2

aHuman lung fibroblast (WI38).

IC50: compound concentration required to inhibit normal cell proliferation by 50% (mean ± SD, n = 3).

IC50 (µM). ϯ1–10 (very strong), *11–25 (strong), 26–50 (moderate), 51–100 (weak), > 100 (non-toxic). DOX doxorubicin as a reference drug.