Table 2.
In vitro cytotoxicity (IC50, µM) of the tested compound and DOX against human normal cell line WI38.
Comp. no. | WI38a IC50 (µM) | Comp. no | WI38 IC50 (µM) |
---|---|---|---|
3 | 78.52 ± 3.8 | 9 | 48.18 ± 2.8 |
5 | 63.97 ± 3.1 | 10 | 67.74 ± 3.4 |
7 | > 100 | 11 | 43.25 ± 2.9 |
8 | 48.18 ± 2.8 | 12 | 56.45 ± 3.2 |
DOX | 4.50 ± 0.2 |
aHuman lung fibroblast (WI38).
IC50: compound concentration required to inhibit normal cell proliferation by 50% (mean ± SD, n = 3).
IC50 (µM). ϯ1–10 (very strong), *11–25 (strong), 26–50 (moderate), 51–100 (weak), > 100 (non-toxic). DOX doxorubicin as a reference drug.