Fig. 2.

Schematic representation of a Cx43 protein in a lipid bilayer membrane. (A) The transmembrane domains TM1, TM2, TM3, and TM4 are represented in blue, red, orange and yellow colors, respectively. (B) The extracellular (EL-1 and EL-2) and cytoplasmic (CL) loops are represented in pink, black, and purple colors, respectively. The amino (NT) and carboxyl (CT) terminus are represented in green and gray colors, respectively. For the sake of clarity, only a small part of the CT domain is represented. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)