Figure 3.

(A,B) Radial growth rate (K_r) for fungi grown at increasing concentrations of paclitaxel in potato dextrose agar (PDA) or Minimal Melin Norkrans (MMN) media. The radial growth rate [K_r = (radius₁-radius₀)/(time₁-time₀)] was calculated as a linear regression (Trinci, 1971). The fungi displayed different radial growth rates, which remained fairly constant when grown in either medium, regardless of the concentration of paclitaxel used. However, the radial growth rate for H. annosum was lower when grown in PDA, while Diaporthe sp. strain PAR5 showed a decrease when grown in MMN. Only the days corresponding to the exponential growth phase (Days 2–5) were included in the calculations. The bars indicate the standard deviation.