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. 2022 Sep 29;9:952599. doi: 10.3389/fvets.2022.952599

Table 1.

The main PK parameters of tilmicosin in lung tissues of the M. gallisepticum infected chickens.

Parameter Units 1 mg/kg 30 mg/kg
t1/2kel h 48.46 50.60
Tmax h 12.00 12.00
Cmax μg/g 0.12 6.19
AUC μg·h/g 13.62 464.23
MRT h 53.60 50.88
CL/F l/h/kg 0.09 0.06

t1/2kel, elimination half-life; tmax, the time of peak concentration; Cmax, the maximum concentration of drug in samples; AUC, the area under the concentration–time curve; MRT, mean residence time; CL/F, clearance divided by bioavailability.