Fig. 5.

F_{ST_MaxSNP} and F_{ST_FullWin} both show outlier enrichment between natural populations of D. melanogaster. (A and B) Ethiopia–Zambia F_{ST_MaxSNP} and F_{ST_FullWin} values on (A) chromosome X and (B) autosomes show enrichment of low (right) and especially high values (left), based on the distribution of P-values obtained from neutral demographic simulations. (C and D) F_{ST_MaxSNP} (lower diagonal) and F_{ST_FullWin} (upper diagonal) both show enrichment of high outliers on (C) chromosome X and (D) combined autosome arms. F_{ST_FullWin} shows a greater enrichment in nearly all cases. (E and F) The number of outlier regions that were removed to erase the signature of enrichment for high F_{ST_MaxSNP} (lower diagonal) and F_{ST_FullWin} (upper diagonal) for each population on (E) chromosome X and (F) the combined autosome arms. F_{ST_FullWin} was associated with a greater outlier region enrichment for most population pairs, reinforcing the window-level patterns shown in (C) and (D). Populations: SD, South Africa; ZI, Zambia; KF, Kafue; RG, Rwanda; EF, Ethiopia. Population pairs that were not present in the same demographic model were not evaluated. Color scale ranges from the minimum to maximum value within each panel.