(A) Correlation of SPARC expression levels with immune cells (CD4+ T cells, macrophages, B cells, CD8+ T cells, neutrophils and dendritic cells) in LUAD. (B) Correlation of SPARC expression levels with immune cells (CD4+ T cells, macrophages, B cells, CD8+ T cells, neutrophils and dendritic cells) in LUSC. The infiltration level is displayed on the X-axis and the expression of SPARC on the Y-axis. (C) Relationship between the degree of immune-cell infiltration and survival prognosis of patients with LUAD. (D) Relationship between the degree of immune-cell infiltration and survival prognosis of patients with LUSC. The time to follow-up (months) is presented on the X-axis and the cumulative survival on the Y-axis. SPARC, secreted protein acidic and cysteine rich; LUAD, lung adenocarcinoma; LUSC, lung squamous cell carcinoma; TPM, transcripts per million; cor, correlation coefficient.