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Membrane characteristics of pyramidal neurons before (vehicle) and after application of various concentrations of TTX.
| Parameter | Vehicle (n = 9) |
3 nM TTX (n = 5) |
10 nM TTX (n = 7) |
30 nM TTX (n = 7) |
|
RMP (mV) |
−67.4 ± 0.7 | −68.8 ± 1.3 | −68.3 ± 1.6 | −68.9 ± 1.6 |
| Rin (MΩ) | 133.7 ± 17.6 | 139.6 ± 21.1 | 113.04 ± 10.4 | 139.3 ± 19.2 |
Data are presents as mean ± SEM. The number of cells tested with each condition is given in parenthesis. RMP, resting membrane potential; Rin, Input resistance.
