TABLE 2.

Sensitivity of TTX on AP firing at different current ramp slopes.

Current ramp slopes	#AP		TTX inhibition of AP firing relative to vehicle (%)
	Vehicle (n = 7)	3 nM TTX (n = 7)
60 pA/s	154 ± 19.5	126.8 ± 19.1*	18.0 ± 6.4
120 pA/s	82.8 ± 9.8	60.8 ± 9.05*	27.2 ± 4.1
240 pA/s	46.8 ± 5.1	32.1 ± 4.6*	32.3 ± 3.2

Data are presents as mean ± SEM. The number of cells tested is given in parenthesis. Asterisk (*) indicate significant difference in the number of APs in 3 nM TTX condition from vehicle at a given ramp slope (two-tail t-test, *p < 0.05).