TABLE 2 ∣.
Comparison of blepharospasm cases with and without subsequent spread.
| Focal blepharospasm N = 87 |
Blepharospasm with subsequent spread N = 137 |
p-value | |
|---|---|---|---|
| Age | 63 ± 10 | 63 ± 10 | 0.91 |
| Age of Onset (years) | 51 ± 13 | 52 ± 13 | 0.74 |
| Duration (years) | 12 ± 13 | 11 ± 14 | 0.63 |
| Sex | |||
| Female | 70% (n = 61) | 68% (n = 93) | 0.17 |
| Race | 0.17 | ||
| Asian | 7% (n = 6) | 2% (n = 3) | |
| Black | 6% (n = 5) | 4% (n = 6) | |
| Other | 8% (n = 7) | 4% (n = 6) | |
| White | 79% (n = 69) | 89% (n = 122) | |
| Family History of Dystonia | 2% (n = 2) | 14% (n = 19) | <0.01 |
| Areas Affected | |||
| Lower Face, Jaw, Tongue | 84% (n = 115) | ||
| Larynx | 16% (n = 22) | ||
| Neck | 63% (n = 86) | ||
| Limbs | 26% (n = 36) | ||
| Trunk | 3% (n = 4) | ||
| Sensory Trick | 42% (n = 37) | 64% (n = 88) | <0.01 |
| BFM Severity | |||
| Upper Face | 4.2 ± 2.5 | 6.1 ± 1.6 | <0.01 |
| Total | 4.2 ± 2.5 | 12.3 ± 8.0 | <0.01 |
| GDRS Severity | |||
| Upper Face | 4.4 ± 2.1 | 6.4 ± 1.9 | <0.01 |
| Total | 4.4 ± 2.1 | 12.6 ± 6.4 | <0.01 |
| BoNT Treatment | 82% (n = 72) | 79% (n = 108) | 0.46 |
| BDI-II Total Score | 5.6 ± 7.2 | 9.0 ± 8.4 | <0.01 |
| LSAS Total Score | 22.4 ± 26.6 | 32.0 ± 29.3 | 0.03 |
This table includes data for a subset of 224 cases in the Dystonia Coalition database who participated in a sub-study in which information regarding site of origin of dystonia was available. Abbreviations: BDI-II, Beck depression inventory version 2; BFM, Burke-Fahn-Marsden dystonia rating scale; BoNT, Botulinum neurotoxin; GDRS, global dystonia rating scale; LSAS, Liebowitz social anxiety scale.