FIG. 5.
Unrooted phylogenetic tree of PFK proteins. The tree is based on distance analysis (neighbor-joining method) of selected available sequences of ATP-PFK and PPi-PFK proteins from the following sources in the National Center for Biotechnology Information database (accession numbers are given in parentheses): B. burgdorferi (D70102), Entamoeba histolytica (S68243), Giardia lamblia (S52081), Solanum tuberosum beta subunit (P21343), S. tuberosum alpha subunit (A36094), Arabidopsis thaliana (AC015450.3), Thermotoga maritima (PPi-PFK) (G72396), Trichomonas vaginalis (AAD13344), Naegleria fowleri (S54978), T. brucei (AAC47836), A. methanolica (ATP-PFK) (AF298119), B. burgdorferi (putative PFK) (F70190), T. pallidum (A71366), Propionibacterium shermanii (A41169), Mycoplasma genitalium (G64223), Thermus thermophilus (P21777), T. maritima (ATP-PFK) (C72406), Aquifex aeolicus (O67605), E. coli (KIECFA), Lactococcus lactis (JN0614), Lactobacillus delbrueckii (A48663), Bacillus subtilis (A69675), Thermoproteus tenax (CAA74985), Dictyoglomus thermophilum (AF268276.1), S. coelicolor A3(2) (PFK1) (OO8333), A. methanolica (PPi-PFK) (Q59126), S. coelicolor A3(2) (putative PFK) PFK2 (AL138978.1), S. coelicolor A3(2) (putative PFK) PFK3 (AL391017.1), M. tuberculosis (O53257), M. leprae (O33106), Saccharomyces cerevisae alpha subunit (NP011756.1), S. cerevisae beta subunit (NP013932), rat (A53047), rabbit (P00125128), and human muscle (227448). Bootstrap values, based on 100 replicates, are indicated at the branch points. The asterisks indicate putative PFKs.