Unrooted phylogenetic tree of PFK proteins. The tree is
based on distance analysis (neighbor-joining method) of selected
available sequences of ATP-PFK and PPi-PFK proteins from
the following sources in the National Center for Biotechnology
Information database (accession numbers are given in parentheses):
B. burgdorferi (D70102), Entamoeba
histolytica (S68243), Giardia lamblia (S52081),
Solanum tuberosum beta subunit (P21343), S.
tuberosum alpha subunit (A36094), Arabidopsis
thaliana (AC015450.3), Thermotoga maritima
(PPi-PFK) (G72396), Trichomonas vaginalis
(AAD13344), Naegleria fowleri (S54978), T.
brucei (AAC47836), A. methanolica (ATP-PFK)
(AF298119), B. burgdorferi (putative PFK)
(F70190), T. pallidum (A71366), Propionibacterium
shermanii (A41169), Mycoplasma genitalium
(G64223), Thermus thermophilus (P21777), T.
maritima (ATP-PFK) (C72406), Aquifex aeolicus
(O67605), E. coli (KIECFA), Lactococcus
lactis (JN0614), Lactobacillus delbrueckii
(A48663), Bacillus subtilis (A69675),
Thermoproteus tenax (CAA74985), Dictyoglomus
thermophilum (AF268276.1), S. coelicolor A3(2)
(PFK1) (OO8333), A. methanolica (PPi-PFK)
(Q59126), S. coelicolor A3(2) (putative PFK) PFK2
(AL138978.1), S. coelicolor A3(2) (putative PFK) PFK3
(AL391017.1), M. tuberculosis (O53257), M.
leprae (O33106), Saccharomyces cerevisae alpha
subunit (NP011756.1), S. cerevisae beta subunit
(NP013932), rat (A53047), rabbit (P00125128), and human muscle
(227448). Bootstrap values, based on 100 replicates, are indicated at
the branch points. The asterisks indicate putative PFKs.