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Key proteins and metabolites profiling in migraine patients after acupuncture treatment could reveal the correlative link between acupuncture and energy metabolism in the context of trigeminovascular system. Proteomics and metabolomics profiles indicated that acupuncture treatments may decrease oxidative stress levels (FAD, BLVRB, L-glutamate) while increasing glucose availability (α-D-glucose), thereby aiding in restoring energy homeostasis.
