Table 4.
Association of the platform’s QT/QTc intervals with the 12-lead electrocardiogram’s QT/QTc intervals.a
|
|
12-lead | Lead I | Lead II | ||||||||||||||||||||||||
|
|
b,c (SE) |
P value |
b,d (SE) |
P value |
b,c (SE) |
P value |
b,d (SE) |
P value |
b,c (SE) |
P value |
b,c (SE) |
P value |
|||||||||||||||
| QTce,f | 0.30 (0.09) | .002 | 0.31 (0.09) | .001 | 0.35 (0.11) | .002 | 0.30 (0.12) | .01 | 0.42 (0.14) | .002 | 0.30 (0.14) | .03 | |||||||||||||||
|
|
Age |
|
|
0.30 (0.22) | .18 |
|
|
0.33 (0.29) | .26 |
|
|
0.04 (0.36) | .92 | ||||||||||||||
|
|
Male |
|
|
–10.66 (6.03) | .08 |
|
|
–10.84 (7.87) | .26 |
|
|
–22.29 (9.41) | .92 | ||||||||||||||
|
|
HRg,h |
|
|
–1.93 (0.52) | <.001 |
|
|
–0.93 (0.43) | .03 |
|
|
–1.62 (0.56) | .006 | ||||||||||||||
| QTf | 0.54 (0.08) | <.001 | 0.53 (0.08) | <.001 | 0.44 (0.10) | <.001 | 0.41 (0.09) | <.001 | 0.52 (0.11) | <.001 | 0.48 (0.12) | <.001 | |||||||||||||||
|
|
Age |
|
|
0.37 (0.24) | .13 |
|
|
0.47 (0.26) | .08 |
|
|
0.19 (0.33) | .58 | ||||||||||||||
|
|
Male |
|
|
0.54 (6.02) | .93 |
|
|
2.03 (6.47) | .75 |
|
|
–8.13 (8.11) | .32 | ||||||||||||||
|
|
HR |
|
|
–0.29 (0.53) | .59 |
|
|
1.09 (0.38) | .006 |
|
|
0.54 (0.53) | .31 | ||||||||||||||
aThe QT/QTc intervals from the 12-lead electrocardiogram were modeled using multiple linear regression with QT/QTc intervals from the platform as the main predictor, adjusted for age, sex, and change in HR.
b
: parameter estimates.
csimple linear regression.
dmultiple linear regression.
eQTc: corrected QT.
fQTc/QT measurements were from the platform.
gHR: heart rate.
hChange in HR between the platform and electrocardiogram.