Figure 5.
No compensatory increase in hormone-expressing endocrine cells in the ILD or PDG compartments of type 1 diabetes (T1D) subjects. Frequency of glucagon+ (A), somatostatin+ (B) and pancreatic polypeptide (PP)+ cells (C) in ILD and PDG compartments. Data are presented as mean ± SEM for T1D (black circles, n = 21) and nondiabetes (ND) donors (blue filled squares, n = 21). Each data point represents an average of 1 to 3 sections per donor (from the pancreatic head, body, and/or tail regions; see Table 1). Unpaired t test, P > 0.05 all.