Table 2. CC50, IC50 (μg/mL), and IS of 6c, 6d, and 8c Compounds with Viral Reduction 50% or More.
| herpes simplex virus | |||||
|---|---|---|---|---|---|
| compd no. | mean % of reduction | nontoxic dose (μg/mL) | CC50 (μg/mL) | IC50 (μg/mL) | IS |
| 6c | 83% | 100 | 1.8 | 0.55 | 3.4 |
| 6d | 80% | 100 | 1.6 | 0.57 | 2.8 |
| 8c | 86% | 100 | 2.0 | 0.57 | 3.5 |
| acyclovir | 99% | - | 2.7 | 0.07 | 4.00 |
| HCVcc genotype virus | |||||
| 6c | 63.3% | 100 | 1.9 | 0.76 | 2.5 |
| 8c | 66.7% | 100 | 1.7 | 0.71 | 2.4 |
| coxsackievirus B4 | |||||
| 6c | 63.3% | 100 | 1.9 | 0.76 | 2.5 |
| 6d | 50.0% | 100 | 1.7 | 1.0 | 1.7 |
| 8c | 66.7% | 100 | 1.7 | 0.69 | 2.4 |