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Vesicle type, designation, and size reduction procedure.
| Sonication time (s) | Sonication intervals | Rounds of extrusion | |
|---|---|---|---|
| PL | 10 | 10 | 3 |
| PL-CHX | 5 | 1 | – |
| CH | 10 | 10 | 3 |
| CH-CHX | 5 | 2 | – |
| CO | 10 | 18 | – |
| CO-CHX | 5 | 1 | – |
PL, Plain, empty lipid carrier; PL-CHX, Plain CHX-lipid carrier; CH, Chitosan-containing empty liposomes; CH-CHX, Chitosan-containing CHX-liposomes; CO, Chitosan-coated empty liposomes; CO-CHX, Chitosan-coated CHX-liposomes.
