Table 4.

Chitosan-containing liposomes and chitosan-coated liposomes stability after 2 and 4 weeks of storage: mean diameter (≤80%, nm), polydispersity index (PI), zeta potential, and pH in aqueous medium.

	Week	Size (80%, nm)	PI	Zeta potential (mV)	pH
PL	2	326 ± 54	0.44 ± 0.05	−2.6 ± 0.6	6.0 ± 0.2
	4	298 ± 25	0.39 ± 0.05	−3.9 ± 0.1	5.7 ± 0.3
PL-CHX	2	272 ± 11	0.41 ± 0.02	40.2 ± 7.6	7.7 ± 0.2
	4	259 ± 8	0.40 ± 0.01	42.2 ± 10.5	7.8 ± 0.4
CH	2	307 ± 19	0.32 ± 0.00	11.1 ± 0.9	3.6 ± 0.0
	4	307 ± 24	0.31 ± 0.01	11.1 ± 0.9	3.7 ± 0.0
CH-CHX	2	285 ± 5	0.28 ± 0.01	92.1 ± 7.8	3.8 ± 0.0
	4	280 ± 6	0.29 ± 0.02	91.9 ± 3.3	3.8 ± 0.0
CO	2	316 ± 17	0.36 ± 0.01	12.5 ± 1.0	3.7 ± 0.0
	4	328 ± 25	0.37 ± 0.01	11.8 ± 0.6	3.7 ± 0.0
CO-CHX	2	375 ± 44	0.39 ± 0.02	83.3 ± 3.2	3.8 ± 0.0
	4	371 ± 40	0.42 ± 0.03	78.6 ± 0.9	3.8 ± 0.0

Vesicle stability after 2 and 4 weeks of storage at 4°C. Results of size measurements are expressed as means of cumulative size ≤80% of vesicle populations (weight-intensity distribution) with their respective SD, while the rest of the results are expressed as means with their respective SD (n = 3), while the rest of the results are expressed as means with their respective SD (n = 3). PL, Plain, empty lipid carrier; PL-CHX, Plain CHX-lipid carrier; CH, Chitosan-containing empty liposomes; CH-CHX, Chitosan-containing CHX-liposomes; CO, Chitosan-coated empty liposomes; and CO-CHX, Chitosan-coated CHX-liposomes.