Table 4.

Investigator assessed RECIST v1.1 response by Dose Level.

	Level 1	Level 2	Level 3	Level 4	All Levels
Complete Response (CR)	0	0	0	0	0
Partial Response (PR)	0	0	0	0	0
Stable Disease (SD)	2/3 (66.7%)	6/20 (30.0%)	2/5 (40.0%)	1/1 (100%)	11/29 (38.0%)
Progressive Disease (PD)	1/3 (33.3%)	14/20 (70.0%)	3/5 (60.0%)	0	17/29 (62.0%)
Overall Response Rate (ORR)	0	0	0	0	0
Median Time to Progression (range)	3.4 months (1.2-10.8)	1.7 months (0.9-5.5)	3.7 months (0.9-6.2)	Not Applicable	–
Median duration of Stable Disease	7.1 months	4.1 months	4.9 months	Not Applicable	–