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. 2022 Sep 29;13:996134. doi: 10.3389/fimmu.2022.996134

Table 1.

Background and SARS-CoV-2 antibody titers of the control and NMDs groups.

Variables Control group NMDs group p value
N 346 11 (SMA, 9; DMD, 2)
Sex (male:female) 60:286 7:4 0.001
Age (years) 40.0 ± 12.4 32.7 ± 19.3 0.062
SARS-CoV-2 antibody titers (U/mL)
 Before vaccination <0.40 <0.40 1.000
 Two weeks after first vaccination 103 ± 1192 145 ± 258 0.909
  Male 26 ± 29 203 ± 312 <0.001
  Female 42 ± 69 42 ± 70 0.998
 Two weeks after second vaccination 1429 ± 944 1528 ± 1265 0.736
  Male 1167 ± 633 1206 ±990 0.886
  Female 1486 ± 991* 2091 ±1646 0.230

DMD: Duchenne muscular dystrophy; NMDs: neuromuscular disorders; SMA: spinal muscular atrophy; *, In the control group, females had significantly higher antibody titers than males after the second vaccination (p = 0.0176).