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. 2022 Oct 13;22:316. doi: 10.1186/s12935-022-02736-2

Table 6.

Notch-associated lncRNAs in relation to metastasis or recurrence in CRC

Notch-associated
lncRNA
CRC Refs.
Notch regulated miR sponged Target protein Recurrence ± 
UICLM miR-215 ZEB2 Liver metastasis [135]
DSCAM-AS1 miR-216b Higher levels are associated with metastasis [128, 213]
LINC00152 miR-185-3p and miR-632

-FSCN1

-E-cadherin & mesenchymal markers vimentin & N-cadherin through interacting with β-catenin

Promotes colon cancer cells invasion & metastasis

[215]

[217]

LINC00707 Notch3 Recurrence [130, 218]