. 2022 Sep 27;12(19):2585. doi: 10.3390/ani12192585

Table 4.

Criteria for a preparation to qualify as a postbiotic Salminem et al. [144].

Criteria for a Preparation to Qualify as a Postbiotic
▪ Molecular characterization of the progenitor microorganisms (for example, fully annotated genome sequence) to enable accurate identification and screen for potential genes of safetyconcern. ▪ Detailed description of the inactivation procedure and the matrix. ▪ Confirmation that inactivation has occurred. ▪ Evidence of a health benefit in the host from a controlled, high- quality trial. ▪ Detailed description of the composition of the postbiotic preparation. ▪ Assessment of safety of the postbiotic preparation in the target host for the intended use.

Criteria for a Preparation to Qualify as a Postbiotic

▪
Molecular characterization of the progenitor microorganisms (for example, fully annotated genome sequence) to enable accurate identification and screen for potential genes of safetyconcern.
▪
Detailed description of the inactivation procedure and the matrix.
▪
Confirmation that inactivation has occurred.
▪
Evidence of a health benefit in the host from a controlled, high- quality trial.
▪
Detailed description of the composition of the postbiotic preparation.
▪
Assessment of safety of the postbiotic preparation in the target host for the intended use.