Skip to main content
. 2022 Sep 28;7(40):35387–35445. doi: 10.1021/acsomega.2c03171

Table 8. Different GO-Based Scaffolds for Cartilage Tissue Engineering.

Entry Scaffolds Biological activity/mechanical properties refs
1 CSMA/PECA/GO CSMA/PECA/GO was not toxic and was biocompatible with favorable breakdown time for cartilage tissue regeneration. (161)
2 Chitosan/PVA/GO polymer Addition of GO increased the nanofiber’s mechanical qualities without compromising its biocompatibility. (21)
3 GO TGF-β3 (growth factor) was adsorbed with no significant conformational change and better stability. (162)
4 GO–PLGA hybrid microparticles Promotes the development of human embryonic cartilage rudiment cells into osteogenic cells. (22)
5 GO-containing chitosan scaffolds Human articular chondrocytes cultured for prolonged periods of time after being deposited on nanocomposite scaffolds showed increased proliferation with increasing GO percent (14 days). (23)
6 GO-incorporated hydrogels Better mechanical strength and compressive modulus as well as continued release of TGF-β3. (163)
7 GO-modified 3D acellular cartilage extracellular matrix scaffold The internal structure and mechanical characteristics of the scaffold are improved by GO modification. In vitro, the GO-modified composite scaffold (2 mg/mL) increases cell adhesion, proliferation, and chondrogenic differentiation. The composite scaffold displayed high biocompatibility and a minimal inflammatory reaction in rats after being implanted subcutaneously. (164)