Table 1.
Q112 antibacterial activity versus Mtb H37Rv.
| Media | MIC a (μM) | |
|---|---|---|
| Day 7 b | Day 14 c | |
| 7H9/cholesterol/dipalmitoylphosphatidylcholine/BSA/Tyloxapol | 0.78 | 1.5 |
| 7H9/cholesterol/BSA/Tyloxapol | 0.78 | 0.78 |
| 7H9/Glucose/BSA/Tyloxapol | 1.5 | 3.12 |
| 7H9/glucose/glycerol/BSA/Tween | 1.5 | 1.5–3.12 |
| GAST/Fe | 1.5 | 1.5 |
| 7H9/2.5mM butyrate/pH6/0.1mM nitrite | 1.2 | 1.6 |
a
MIC, minimal inhibitory concentration.
b
Day 7, growth assessed after 7 days exposure to drug;
c
Day 14, growth assessed after 14 days exposure to drug. Media are described in Experimental Procedures.