Table 4.

Top 10 most published definitions of Low Cardiac Output Syndrome (LCOS) and corresponding incidence rates in an intraoperative cohort with adults, children and infants.

Top 10 LCOS definitions (see Table 3 for definitions)	Adults (N = 5,934)		Children (N = 690)		Infants (N = 742)
	No. of patients without missing data	Incidence LCOS in %	No. of patients without missing data	Incidence LCOS in %	No. of patients without missing data	Incidence LCOS in %
1	400	1.5	0	–	0	–
2*	5,667	8.3	516	23.8	534	30.1
3*	5,667	31.5	516	27.4	534	32.3
4	2,049	12.3	688	5.1	739	16.3
5**	–	–	–	–	–	–
6*	3,365	13.7	542	6.4	571	14.4
7	0	–	0	–	0	–
8	414	1.8	0	–	0	–
9	5,934	91.0	690	55.7	742	82.2
10	5,934	4.5	690	0.6	742	0.4

^*For systolic hypotension and tachycardia we used for children and infants the p-values (91, 92). The p5 for systolic hypotension and p90 for tachycardia.

^**Intensive care follow-up data was not available (e.g., maximum duration of inotropic support). Hence, we could not determine the incidence of LCOS using this definition.

LCOS, low cardiac output syndrome.