Fig. 1.

Cutaneous and histological manifestations of patient case of mycosis fungoides associated with neutrophilic dermatosis. (a) December 2020: erythematous, violaceous patches and plaques. (b) One month later: ulcerated nodules on the buttocks. (c) Clinical remission after 1 month of treatment with brentuximab venodin. (d) Mycosis fungoides recurrence: voluminous nodule on the arm with large pustules. Haematoxylin and eosin stain with (e) dermal infiltrate consisting of numerous atypical lymphocytes and admixed lymphocytes, without oedema in the upper dermis, (f) as well as neutrophils and eosinophils. (g) CD3 immunohistochemistry confirms that malignant cells are of T-cell origin. (h) Large cells transformation, with partial expression of CD30 in immunohistochemistry (approximately 30%).