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Effects of oxostephanine and VX-680 on the expression of Aurora kinase B in mitotic cells. The Aurora B distribution was determined on living HeLa cells stably expressing Aurora B-GFP and on fixed HeLa cells. Of note, in the control cells, this protein was located as bright dots on chromosomes at the metaphase; in treated cells, the protein was diffused in the whole chromosomes, particularly in VX-680-treated cells.
