. 2022 Sep 20;12(19):2496. doi: 10.3390/ani12192496

Table 9.

Effects of treatments on histomorphological ileal parameters at 7 and 14 days post-inoculation with the coccidial inoculum (Experiment 2).

		Experimental Treatments ¹			Statistics
	Age	NC	CC	DC	SEM	p-Value
Villus
Height, µm	14 d	508	506	508	19.53	0.994
Height, µm	21 d	637	582	619	22.34	0.103
Goblet cells/villus	14 d	80.7	85.7	86.5	4.621	0.498
Goblet cells/villus	21 d	85.6 ^a	71.0 ^b	86.1 ^a	3.159	0.001
IEL/villus	14 d	17.7	16.6	19.0	1.476	0.359
IEL/villus	21 d	16.6	14.5	17.5	1.209	0.129
Crypt
Depth, µm	14 d	174 ^b	182 ^ab	196 ^a	6.066	0.019
Depth, µm	21 d	148	159	164	5.598	0.114
Mitotic cells/crypt	14 d	1.35	1.37	1.36	0.193	0.995
Mitotic cells/crypt	21 d	0.91	1.25	1.26	0.160	0.182
Villus:crypt ratio
	14 d	2.98 ^x	2.87 ^xy	2.63 ^y	0.118	0.075
	21 d	4.49 ^a	3.79 ^b	3.91 ^ab	0.233	0.048

¹ NC = non-challenged; CC = control-challenged (coccidiosis); DC = DIC-supplemented-challenged (1 kg/t DIC). Values are means of 12 replicates. A-B Means within a row lacking a common superscript differ (p ≤ 0.01). ^a–b Means within a row lacking a common superscript differ (p ≤ 0.05). ^x–y Means within a row lacking a common superscript differ (0.05 < p ≤ 0.10). DIC = feed additive DICOSAN+; IEL = intraepithelial lymphocytes; SEM = standard error of the mean.